The Wyoming Highway Patrol seized about 123 pounds of marijuana with an estimated street value of $307,000 following a traffic stop on US 220 near Casper on Thursday.
Troopers arrested Thong Xiong, 29, and his passenger, Choua Khang, 30, both from Wisconsin after clocking their vehicle going 71 miles per hour in a 65 mile per hour area.
Xiong said he was traveling from California to South Dakota before heading home to Wisconsin. When troopers questioned the passenger about their travel plans, she gave a conflicting story.
Troopers also saw several boxes and deployed a canine unit after Xiong admitted to having drugs in the vehicle.
Troopers found about 111 individual vacuum-sealed packages containing marijuana. The packages were in a large box, a modified washing machine and a purse.
The Wyoming Division of Criminal Investigation (DCI) are assisting the investigation.
Thong and Khang were taken to the Natrona County Detention Center.